John Piwinski: search on Z-Library

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1

Lumbar Puncture Technique and Lumbar Drains

Sladky, John H., Piwinski, Stephen E.

Journal:

Atlas of the Oral and Maxillofacial Surgery Clinics

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

2

Preparation of Oxime Dual NK1/NK2 Antagonists with Reduced NK3 Affinity.

Gregory A. Reichard, Cheryl A. Grice, Neng-Yang Shih, James Spitler, Sapna Majmundar, Steven D. Wang, Sunil Paliwal, John C. Anthes, John J. Piwinski

Journal:

Year:

2002

File:

PDF, 31 KB

2002

3

Preparation of oxime dual NK1/NK2 antagonists with reduced NK3 affinity

Gregory A Reichard, Cheryl A Grice, Neng-Yang Shih, James Spitler, Sapna Majmundar, Steven D Wang, Sunil Paliwal, John C Anthes, John J Piwinski

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 122 KB

english, 2002

4

Discovery of oxazole-based PDE4 inhibitors with picomolar potency

Rongze Kuang, Ho-Jane Shue, Li Xiao, David J. Blythin, Neng-Yang Shih, Xiao Chen, Danlin Gu, John Schwerdt, Ling Lin, Pauline C. Ting, Jianhua Cao, Robert Aslanian, John J. Piwinski, Daniel Prelusky,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.15 MB

english, 2012

5

A Novel Pyrrolidine Analog of Histamine as a Potent, Highly Selective Histamine H3 Receptor Agonist

Shih, Neng-Yang, Lupo, Andrew T., Aslanian, Robert, Orlando, Steven, Piwinski, John J., Green, Michael J., Ganguly, Ashit K., Clark, Michael A., Tozzi, Salvatore

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 999 KB

english, 1995

6

Novel histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine scaffold

Wayne D. Vaccaro, Rosy Sher, Michael Berlin, Neng-Yang Shih, Robert Aslanian, John H. Schwerdt, Kevin D. McCormick, John J. Piwinski, Robert E. West Jr., John C. Anthes, Shirley M. Williams, Ren-Long

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 161 KB

english, 2006

7

Erratum to “Reduction of CYP450 inhibition in the 4-[(1H-imidazol-4-yl)methyl]piperidine series of histamine H3 receptor antagonists” [Bioorg. Med. Chem. Lett. 16 (2006) 989–994]

Michael Berlin, Pauline C. Ting, Wayne D. Vaccaro, Robert Aslanian, Kevin D. McCormick, Joe F. Lee, Margaret M. Albanese, Mwangi W. Mutahi, John J. Piwinski, Neng-Yang Shih, Luli Duguma, Daniel M. Sol

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 55 KB

english, 2006

8

Interception of the Cope chairlike transition-state product during the tandem Cope-Claisen rearrangement: a route to an ambrosanolide synthon

Ziegler, Frederick E., Piwinski, John J.

Journal:

Journal of the American Chemical Society

Year:

1980

Language:

english

File:

PDF, 269 KB

english, 1980

9

Cyclic urea derivatives as potent NK1 selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions

Ho-Jane Shue, Xiao Chen, John H. Schwerdt, Sunil Paliwal, David J. Blythin, Ling Lin, Danlin Gu, Cheng Wang, Gregory A. Reichard, Hongwu Wang, John J. Piwinski, Ruth A. Duffy, Jean E. Lachowicz, Vicki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 151 KB

english, 2006

10

Identification of a novel 1′-[5-((3,5-Dichlorobenzoyl)methylamino)-3-(3,4-dichlorophenyl)-4-(methoxyimino)pentyl]-2-oxo-(1,4′-bipiperidine) as a Dual NK1/NK2 antagonist

Pauline C Ting, Joe F Lee, Neng-Yang Shih, John J Piwinski, John C Anthes, Richard W Chapman, Charles A Rizzo, John A Hey, Kwokei Ng, Amin A Nomeir

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 110 KB

english, 2002

11

Synthesis and structure–activity relationships of oxime neurokinin antagonists: discovery of potent arylamides

Neng-Yang Shih, Margaret Albanese, John C Anthes, Nicholas I Carruthers, Cheryl A Grice, Ling Lin, Pietro Mangiaracina, Gregory A Reichard, John Schwerdt, Vera Seidl, Shing-Chung Wong, John J Piwinski

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 160 KB

english, 2002

12

Discovery of novel nonpeptide tricyclic inhibitors of ras farnesyl protein transferase

F.George Njoroge, Ronald J. Doll, Bancha Vibulbhan, Carmen S. Alvarez, W.Robert Bishop, Joanne Petrin, Paul Kirschmeier, Nicholas I. Carruthers, Jesse K. Wong, Margaret M. Albanese, John J. Piwinski,

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 1.24 MB

english, 1997

13

Angiotensin converting enzyme inhibitors. 9. Novel [[N-(1-carboxyl-3-phenylpropyl)amino]acyl]glycine derivatives with diuretic activity

Barton, Jeffrey N., Piwinski, John J., Skiles, Jerry W., Regan, John R., Menard, Paul R., Desai, Rohit, Golec, F. S., Reilly, Laurence W., Goetzen, Thomas

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 829 KB

english, 1990

14

A synthesis of N-substituted 1,2-dihydropyridines

Bonfiglio, John N., Hasan, Iltifat, Piwinski, John J., Weinstein, Barry, Fowler, Frank W.

Journal:

Journal of the American Chemical Society

Year:

1976

Language:

english

File:

PDF, 252 KB

english, 1976

15

A Useful Pd-Catalyzed Negishi Coupling Approach to Benzylic Sulfonamide Derivatives

Zhou, Gang, Ting, Pauline, Aslanian, Robert, Piwinski, John J.

Journal:

Organic Letters

Year:

2008

Language:

english

File:

PDF, 133 KB

english, 2008

16

New directions in antihistamine research

Aslanian, Robert, Piwinski, John J

Journal:

Expert Opinion on Therapeutic Patents

Year:

1997

Language:

english

File:

PDF, 334 KB

english, 1997

17

Hydroxylated metabolites of loratadine: an example of conformational diastereomers due to atropisomerism

Piwinski, John J., Wong, Jesse K., Chan, Tze Ming, Green, Michael J., Ganguly, Ashit K.

Journal:

Journal of Organic Chemistry

Year:

1990

Language:

english

File:

PDF, 1.39 MB

english, 1990

18

[Annual Reports in Medicinal Chemistry] Volume 22 || Chapter 8 Pulmonary and Antiallergy Agents

Piwinski, John J.

Year:

1987

Language:

english

File:

PDF, 938 KB

english, 1987

19

ChemInform Abstract: The Design and Synthesis of Novel NK1/NK2 Dual Antagonists.

Gregory A. Reichard, Zachary T. Ball, Robert Aslanian, John C. Anthes, Neng-Yang Shih, John J. Piwinski

Journal:

Year:

2001

File:

PDF, 34 KB

2001

20

Dual antagonists of platelet-activating factor and histamine. Identification of structural requirements for dual activity of N-acyl-4-(5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidines

Piwinski, John J., Wong, Jesse K., Green, Michael J., Ganguly, Ashit K., Billah, M. Motasim, West, Robert E., Kreutner, William

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 584 KB

english, 1991

21

Asymmetric Synthesis of 4,4-Disubstituted-2-Imidazoli-dinones: Potent NK 1 Antagonists

Reichard, Gregory A., Stengone, Carmine, Paliwal, Sunil, Mergelsberg, Ingrid, Majmundar, Sapna, Wang, Cheng, Tiberi, Robert, McPhail, Andrew T., Piwinski, John J., Shih, Neng-Yang

Journal:

Organic Letters

Year:

2003

Language:

english

File:

PDF, 93 KB

english, 2003

22

Synthesis of substituted 4(Z)-(methoxyimino)pentyl-1-piperidines as dual NK1/NK2 inhibitors

Pauline C Ting, Joe F Lee, John C Anthes, Neng-Yang Shih, John J Piwinski

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 154 KB

english, 2001

23

Synthesis and study of N-substituted 1,2-dihydropyridines

Beeken, Paul, Bonfiglio, John N., Hasan, Iltifat, Piwinski, John J., Weinstein, Barry, Zollo, Kenneth A., Fowler, Frank W.

Journal:

Journal of the American Chemical Society

Year:

1979

Language:

english

File:

PDF, 743 KB

english, 1979

24

ChemInform Abstract: A SYNTHESIS OF N-SUBSTITUTED 1,2-DIHYDROPYRIDINES

BONFIGLIO, JOHN N., HASAN, ILTIFAT, PIWINSKI, JOHN J., WEINSTEIN, BARRY, FOWLER, FRANK W.

Journal:

Chemischer Informationsdienst

Year:

1976

File:

PDF, 145 KB

1976

25

Identification of a Dual Histamine H1/H3 Receptor Ligand Based on the H1 Antagonist Chlorpheniramine.

Robert Aslanian, Mwangi wa Mutahi, Neng-Yang Shih, John J. Piwinski, Robert West, Shirley M. Williams, Susan She, Ren-Long Wu, John A. Hey

Journal:

Year:

2003

File:

PDF, 145 KB

2003

26

ChemInform Abstract: Identification of a Novel 1′-[5-((3,5-Dichlorobenzoyl)methylamino)-3-(3,4-dichlorophenyl)-4- (methoxyimino)pentyl]-2-oxo-(1,4′-bipiperidine) (I) as a Dual NK1/NK2 Antagonist.

Pauline C. Ting, Joe F. Lee, Neng-Yang Shih, John J. Piwinski, John C. Anthes, Richard W. Chapman, Charles A. Rizzo, John A. Hey, Kwokei Ng, Amin A. Nomeir

Journal:

Year:

2002

File:

PDF, 31 KB

2002

27

Discovery of a highly potent series of oxazole-based phosphodiesterase 4 inhibitors

Rongze Kuang, Ho-Jane Shue, David J. Blythin, Neng-Yang Shih, Danlin Gu, Xiao Chen, John Schwerdt, Ling Lin, Pauline C. Ting, Xiaohong Zhu, Robert Aslanian, John J. Piwinski, Li Xiao, Daniel Prelusky,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 237 KB

english, 2007

28

Structural characterization of in vitro rat liver microsomal metabolites of antihistamine desloratadine using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange HR-LC/MS

Guodong Chen, Ibrahim Daaro, Birendra N. Pramanik, John J. Piwinski

Journal:

Journal of Mass Spectrometry

Year:

2009

Language:

english

File:

PDF, 216 KB

english, 2009

29

Additions and Corrections - A Synthesis of N-Substituted 1,2-Dihydropyridines

Bonfiglio, John, Hasan, Iltifat, Piwinski, John, Weinstein, Barry, Fowler, Frank

Journal:

Journal of the American Chemical Society

Year:

1976

Language:

english

File:

PDF, 151 KB

english, 1976

30

ChemInform Abstract: Synthesis of Substituted 4-(Z)-(Methoxyimino)pentyl-1-piperidines as Dual NK1/NK2 Inhibitors.

Pauline C. Ting, Joe F. Lee, John C. Anthes, Neng-Yang Shih, John J. Piwinski

Journal:

Year:

2001

File:

PDF, 31 KB

2001

31

ChemInform Abstract: Synthesis and NK1/NK2 Receptor Activity of Substituted-4(Z)-(methoxyimino)pentyl-1-piperazines.

Pauline C. Ting, Joe F. Lee, John C. Anthes, Neng-Yang Shih, John J. Piwinski

Journal:

Year:

2001

File:

PDF, 35 KB

2001

32

Benzimidazole-substituted (3-phenoxypropyl)amines as histamine H3 receptor ligands

Robert Aslanian, Xiaohong Zhu, Henry A. Vaccaro, Neng-Yang Shih, John J. Piwinski, Shirley M. Williams, Robert E. West Jr.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 194 KB

english, 2008

33

Reduction of CYP450 inhibition in the 4-[(1H-imidazol-4-yl)methyl]piperidine series of histamine H3 receptor antagonists

Michael Berlin, Pauline C. Ting, Wayne D. Vaccaro, Robert Aslanian, Kevin D. McCormick, Joe F. Lee, Margaret M. Albanese, Mwangi W. Mutahi, John J. Piwinski, Neng-Yang Shih, Luli Duguma, Daniel M. Sol

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 267 KB

english, 2006

34

Identification of a dual histamine H1/H3 receptor ligand based on the H1 antagonist chlorpheniramine

Robert Aslanian, Mwangi wa Mutahi, Neng-Yang Shih, John J. Piwinski, Robert West, Shirley M. Williams, Susan She, Ren-Long Wu, John A. Hey

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 152 KB

english, 2003

35

Discovery and preliminary pharmacology of Sch 37370, a dual antagonist of PAF and histamine

M. Motasim Billah, Robert W. Egan, Ashit K. Ganguly, Michael J. Green, William Kreutner, John J. Piwinski, Marvin I. Siegel, Frank J. Villani, Jesse K. Wong

Journal:

Year:

1991

Language:

english

File:

PDF, 318 KB

english, 1991

36

Tandem Cope-Claisen rearrangement: a contrathermodynamic [3,3] sigmatropic sequence

Ziegler, Frederick E., Piwinski, John J.

Journal:

Journal of the American Chemical Society

Year:

1979

Language:

english

File:

PDF, 273 KB

english, 1979

37

Challenges in Modern Drug Discovery: A Case Study of Boceprevir, an HCV Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

Njoroge, F. George, Chen, Kevin X., Shih, Neng-Yang, Piwinski, John J.

Journal:

Accounts of Chemical Research

Year:

2008

Language:

english

File:

PDF, 1.06 MB

english, 2008

38

[Annual Reports in Medicinal Chemistry] Volume 34 || Chapter 7. Recent Approaches Towards Inhibiting Allergic Eosinophilia

Piwinski, John J.

Year:

1999

Language:

english

File:

PDF, 810 KB

english, 1999

39

Structural determinants for histamine H1 affinity, hERG affinity and QTc prolongation in a series of terfenadine analogs

Robert Aslanian, John J. Piwinski, Xiaohong Zhu, Tony Priestley, Steve Sorota, Xiao-Yi Du, Xue-Song Zhang, Robbie L. McLeod, Robert E. West, Shirley M. Williams, John A. Hey

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 1.17 MB

english, 2009

40

Novel TNF-α converting enzyme (TACE) inhibitors as potential treatment for inflammatory diseases

Vinay M. Girijavallabhan, Lei Chen, Chaoyang Dai, Robert J. Feltz, Luke Firmansjah, Dansu Li, Seong Heon Kim, Joseph A. Kozlowski, Brian J. Lavey, Aneta Kosinski, John J. Piwinski, Janeta Popovici-Mul

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 666 KB

english, 2010

41

Trans-4-methyl-3-imidazoyl pyrrolidine as a potent, highly selective histamine H3 receptor agonist in vivo

Neng-Yang Shih, Robert Aslanian, Andrew T. Lupo Jr., Steve Orlando, John J. Piwinski, Michael J. Green, Ashit K. Ganguly, Robert West, Salvatore Tozzi, William Kreutner, John A. Hey

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 260 KB

english, 1998

42

ChemInform Abstract: Dual Antagonists of Platelet Activating Factor and Histamine. Part 3. Synthesis, Biological Activity and Conformational Implications of Substituted N-Acyl-bis-arylcycloheptapiperazines.

John J. Piwinski, Jesse K. Wong, Michael J. Green, James J. Kaminski, Frank Colizzo, Margaret M. Albanese, Ashit K. Ganguly, M. Motasim Billah, John C. Anthes, Robert E. West Jr.

Journal:

Year:

1999

File:

PDF, 31 KB

1999

43

Cyclic urea derivatives as potent NK1 selective antagonists

Ho-Jane Shue, Xiao Chen, Neng-Yang Shih, David J. Blythin, Sunil Paliwal, Ling Lin, Danlin Gu, John H. Schwerdt, Sapna Shah, Gregory A. Reichard, John J. Piwinski, Ruth A. Duffy, Jean E. Lachowicz, Vi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 223 KB

english, 2005

44

Identification of a novel, orally bioavailable histamine H3 receptor antagonist based on the 4-benzyl-(1H-imidazol-4-yl) template

Robert Aslanian, Mwangi W. Mutahi, Neng-Yang Shih, Kevin D. McCormick, John J. Piwinski, Pauline C. Ting, Margaret M. Albanese, Michael Y. Berlin, Xiaohong Zhu, Shing-Chun Wong, Stuart B. Rosenblum, Y

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 150 KB

english, 2002

45

New Applications of PhI(OAc)2 in Synthesis: Total Synthesis and SAR Development of Potent Antitumor Natural Product Psymberin/Irciniastatin A

Shao, Ning, Huang, Xianhai, Palani, Anandan, Aslanian, Robert, Buevich, Alexei, Piwinski, John, Huryk, Robert, Seidel-Dugan, Cynthia

Journal:

Year:

2009

Language:

english

File:

PDF, 378 KB

english, 2009

46

Triaryl Bis-sulfones as a New Class of Cannabinoid CB2 Receptor Inhibitors: Identification of a Lead and Initial SAR Studies.

Brian J. Lavey, Joseph A. Kozlowski, R. William Hipkin, Waldemar Gonsiorek, Daniel J. Lundell, John J. Piwinski, Satwant Narula, Charles A. Lunn

Journal:

Year:

2005

File:

PDF, 21 KB

2005

47

The design and synthesis of novel NK1/NK2 dual antagonists

Gregory A Reichard, Zachary T Ball, Robert Aslanian, John C Anthes, Neng-Yang Shih, John J Piwinski

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 188 KB

english, 2000

48

Dual antagonists of platelet activating factor and histamine. 2. pyridine ring substitution of N-acetyl-4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidines

Jesse K. Wong, John J. Piwinski, Michael J. Green, Ashit K. Ganguly, John C. Anthes, M.Motasim Billah

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 418 KB

english, 1993

49

Pyridofuran substituted pyrimidine derivatives as HCV replication (replicase) inhibitors

Frank Bennett, Hollis S. Kezar III, Vinay Girijavallabhan, Yuhua Huang, Regina Huelgas, Randall Rossman, Neng-Yang Shih, John J. Piwinski, Malcolm MacCoss, Cecil D. Kwong, Jeremy L. Clark, Anita T. Fo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 2.52 MB

english, 2012

50

Stereochemical course of the Cope-Claisen rearrangement of the stereoisomeric 2-vinyl-3-isopropenylcyclohexylvinyl ethers. A system having .DELTA.GClaisen.++. .mchgt. .DELTA.GCope.++.

Ziegler, Frederick E., Piwinski, John J.

Journal:

Journal of the American Chemical Society

Year:

1980

Language:

english

File:

PDF, 367 KB

english, 1980

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